Synulox 500mg 100 tablets | antibiotic for large dogs

SYNULOX 500 Appetizing Tablets Antibacterial oral tablet

Laboratory
PFIZER, SA
Pharmaceutical form
Oral tablet (Comp.o.)
Composition by tablet:
Amoxicillin (trihydrate) 400 mg; clavulanic acid (potassium clavulanate) 100 mg.
Pharmacological properties
Synulox 500 Appetizing Tablets is an association of antibacterials whose justification is based
in the broadening of the spectrum activity of amoxicillin against germs that produce â
-lactamases. Amoxicillin is a semisynthetic penicillin that prevents cell wall synthesis.
bacteria by inhibition of transpeptidases and carboxypeptidases enzymes, causing a
osmotic imbalance that destroys the bacteria in the growth phase. clavulanic acid is
an antibacterial inhibitor of â-lactamases with little intrinsic antimicrobial action. The
The inhibition that occurs is progressive and irreversible, as a stable complex is formed.
molecule-enzyme. During this process clavulanic acid is destroyed. In this way it prevents
the â-lactam ring of amoxicillin is broken and may lose activity.
Interactions and incompatibilities
Do not administer together with bacteriostatic anti-infectives.
Indications and target species
big dogs: Infections caused by sensitive germs located in: digestive tract,
respiratory tract, urogenital tract, skin and soft tissues; as well as bacterial complications
sensitive to amoxicillin in diseases that require it.
Contraindications
• Do not administer to animals with a history of allergy to â-lactam antibacterials.
• Do not administer to rabbits, guinea pigs and hamsters.
efectos secundarios
• Sensitization reactions whose severity can vary from a simple urticaria to a
anaphylactic shock.
• Mild gastrointestinal symptoms.
• Supra-infections by non-susceptible microorganisms after prolonged use. may occasionally
produce hematic dyscrasias and colitis.
Route of administration
Orally.
Posology
big dogs: 12,50 mg/kg bw, twice a day, which is equivalent to 1 tablet/40 kg of bw
per dose twice daily.
• It is recommended not to extend the treatment more than 5-7 days.
Wait time
Not applicable.
conservation mode
Store in a cool, dry place and protected from light, at a temperature not exceeding 25 °C.
Comments
With veterinary prescription.
Presentation
Boxes with 10 and 100 tablets.
Reg No.
0840-ENG

See technical sheet

Synulox